核醫學和生物學旨在為描述原始合成、體外組織研究或體內使用放射性示蹤劑、放射性藥物或治療劑的原始研究貢獻。論文集中于合成、體外試驗和體內化合物的檢測。廣泛的研究證明了在體內定位的機制，無論是基于受體，酶，或腫瘤抗原結合或其他明確定義的過程是每一個評估的一個組成部分。此外，研究應確定一個重要的化合物，是一個敏感的探針的生化變化在體內。

Nuclear Medicine and Biology is intended for original research contributions describing original synthesis, in vitro tissue studies, or in vivo use of radiotracers, radiopharmaceuticals, or therapeutic agents. Papers concentrate on the synthesis, testing in vitro, and examination of a compound in vivo. Extensive studies proving the mechanism of localization in vivo whether the radioactive substance is based on receptor-, enzyme-, or tumor antigen-binding or other well defined processes are an integral part of each evaluation. Additionally, studies should define a significant compound that is a sensitive probe of a biochemical change in vivo.