《微生物學與免疫學》是一本多學科期刊，旨在為微生物和宿主免疫、生物和生理反應以及治療學的研究提供深入的見解。該雜志以高質量的原創文章形式發表重要成果的報告，并對細菌學、病毒學、免疫學及相關領域的前沿研究進行了評述;人類、包括無脊椎動物和植物在內的各種動物的致病性感染;微生物毒素、細胞表面成分等致病性和毒力因子;參與宿主防御、炎癥、疫苗研制的因素;抗菌藥物和微生物耐藥性;基因組學和蛋白質組學。微生物學和免疫學也以評論和微型評論文章為特色，針對更廣泛的受眾，而不局限于這些領域的研究人員。

Microbiology and Immunology is a multidisciplinary journal aimed at providing insight into the study of microbes and the host immune, biological and physiological responses, and therapeutics.The journal publishes reports of significant results as high quality original articles and notes dealing with advanced research in all fields of bacteriology, virology, and immunology, and related fields; pathogenic infections in humans, various animals including invertebrates, and plants; pathogenicity and virulence factors such as microbial toxins and cell-surface components; factors involved in host defense, inflammation, development of vaccines; antimicrobial agents and drug resistance of microbes; genomics and proteomics.Microbiology and Immunology also features review and mini-review articles targeted broader audience, not limited to researchers in these fields.