《醫學信息方法》論述了醫學和衛生保健中處理數據、信息和知識的基本方法和科學基礎。它出版醫學信息學和醫學生物計量學等相關學科的原始論文、評論、報告、意見論文和社論。自1962年該雜志成立以來，信息處理方法和信息通信技術的進步極大地改變了我們的社會，醫學和衛生保健利用了這一進步。《醫學信息方法》發表的論文涉及醫學和衛生保健領域的整個數據處理、信息和知識領域，包括傳統領域和這一不斷擴大的領域的新領域的研究。它包括健康信息系統和病人記錄等主題;衛生保健中的診斷和治療;生物醫學數據、信號和圖像解釋;臨床生物信息學;臨床資料分析與統計研究;專家系統和知識表示;仿真和建模。

Methods of Information in Medicine discusses the basic methodology and scientific fundamentals of processing data, information and knowledge in medicine and health care. It publishes original papers, reviews, reports, opinion papers, and editorials in medical informatics, and related disciplines such as medical biometry. Since the Journal's foundation in 1962, progress in information processing methodology and in information and communication technology has greatly changed our societies, and medicine and health care have taken advantage of this progress. Methods of Information in Medicine publishes papers in the whole range of processing data, information and knowledge in medicine and health care, including research in traditional and in new areas of this expanding field. It includes topics such as health information systems and patient records; diagnosis and therapy in health care; biomedical data, signal, and image interpretation; clinical bioinformatics; clinical data analysis and statistical studies; expert systems and knowledge representation; simulation and modeling.