《美國質譜學會雜志》發表了涵蓋質譜學各個方面的研究論文，包括質譜學可以發揮作用的科學研究領域。綜合范圍，該雜志發表論文的基礎和質譜應用。基礎學科包括儀器原理、設計和演示、氣相離子的結構和化學性質、熱力學性質研究、離子光譜學、化學動力學、電離機理、離子碎裂理論、團簇離子和勢能表面。除了完整的論文外，該雜志還提供通信、應用說明、賬目和觀點。所有的論文都應該描述新的質譜學。使用標準質譜方法的應用報告應發送到應用期刊。

The Journal of the American Society for Mass Spectrometry presents research papers covering all aspects of mass spectrometry, incorporating coverage of fields of scientific inquiry in which mass spectrometry can play a role.Comprehensive in scope, the journal publishes papers on both fundamentals and applications of mass spectrometry. Fundamental subjects include instrumentation principles, design, and demonstration, structures and chemical properties of gas-phase ions, studies of thermodynamic properties, ion spectroscopy, chemical kinetics, mechanisms of ionization, theories of ion fragmentation, cluster ions, and potential energy surfaces. In addition to full papers, the journal offers Communications, Application Notes, and Accounts and Perspectives. All papers should describe new mass spectrometry science. Reports of applications that utilize standard mass spectrometry approaches should be sent to application journals.