臨床化學是當今臨床實驗室進行同行評審、原創研究的領先論壇。在臨床化學、臨床(或解剖)病理學、分析化學、輸血醫學、臨床微生物學等分支學科期刊中，Clin Chem除了是該領域被引用最多的期刊(2005年被引用超過18000次)外，其影響因子最高(2005年為7.717)。該雜志每月出版一期，發表有關基本材料或原理、分析和分子診斷技術、儀器儀表、數據處理、數據統計分析、化學在其中發揮重要作用的臨床研究或針對人類疾病的化學問題的實驗室動物研究的實驗或理論貢獻。

Clinical Chemistry is the leading forum for peer-reviewed, original research on innovative practices in today s clinical laboratory. In addition to being the most cited journal in the field (over 18,000 citations in 2005), Clin Chem has the highest Impact Factor (7.717 in 2005) among journals of clinical chemistry, clinical (or anatomic) pathology, analytical chemistry, and the subspecialties, such as transfusion medicine, clinical microbiology. The journal issued monthly, publishes contributions, either experimental or theoretical, that concern basic materials or principles, analytical and molecular diagnostic techniques, instrumentation, data processing, statistical analyses of data, clinical investigations in which chemistry has played a major role, or laboratory animal studies of chemically oriented problems of human disease.