發表關于真核細胞細胞核功能組織的研究和綜述文章，特別強調染色質和染色體的結構和動力學;基因組的表達和復制;基因組組織與進化;在減數分裂和有絲分裂過程中基因組的分離;亞核室的功能和動力學;核膜和核質相互作用，等等。

Chromosoma publishes research and review articles on the functional organization of the eukaryotic cell nucleus, with a particular emphasis on the structure and dynamics of chromatin and chromosomes; the expression and replication of genomes; genome organization and evolution; the segregation of genomes during meiosis and mitosis; the function and dynamics of subnuclear compartments; the nuclear envelope and nucleocytoplasmic interactions, and more.