本雜志發表了關于抗菌、抗病毒和抗腫瘤物質的作用模式和藥理特性的研究結果。雖然以實驗工作為主，但也包括臨床研究。為該雜志挑選的論文提供了有關新藥在單獨和聯合應用中的有效性、毒理學和相互作用的數據。該雜志還發表了旨在確定藥物動力學特性或評估類似制劑的比較療效的研究。通過在每期雜志和定期增刊上發表大量關于抗生素和細胞抑制劑化療的專題文章，化療應用的增長得到了很好的服務。

This journal publishes the results of investigations into the mode of action and pharmacologic properties of antibacterial, antiviral and antitumor substances. Although experimental work predominates, clinical studies are included. Papers selected for the journal offer data concerning the efficacy, toxicology, and interaction of new drugs in single and combined applications. The journal also publishes studies designed to determine pharmacokinetic properties or evaluate the comparative efficacy of similar preparations. The growth of chemotherapeutic applications is well served through the large number of contributions published in each issue and regular supplement issues devoted to specific themes concerning antibiotic and cytostatic chemotherapy.